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Prednisolone is a steroidal medication. It used as anti-inflammatory agent and immunosuppressant medication for the treatment of autoimmune disorders. It is taken orally to treat allergic reactions of various origins such as skin conditions, psoriasis, inflammation, asthma, arthritis, breathing ailment, lupus, ulcerative colitis  and other allergic and skin conditions. It calm down over active immune response.


How Prednisolone Works?

The anti-inflammatory actions of Prednisolone involve suppression of  humoral immune responses. Prednisolone belongs to the class of medication known as Glucocorticosteroids that can reduce leukocyte permeation at the site of inflammation. It causes profound metabolic effects which control the biosynthesis of intoxicating mediators of responsible for the inflammation. These include suppression of such as prostaglandins and leukotrienes. It diminishes the inflammatory reaction by forbidding the capillary dilatation and permeability of the vascular configuration.


The Dosing Schedule for the Drug -

The Prednisolone is available in strength 5mg, 10mg, and 20mg tablet in form of dispersible tablets. The medicine is orally devoured is via mouth with sufficient amount of water, if possible with food. Take medicine once a day or else follow the dosage as recommended by your physician. Consult the doctor before starting Prednisolone regimen.


Is there any health risk of Prednisolone Administration?

The side effects may range from severe to moderate in case of ill administration and over dosing. Some commonly occurring harmful effects are dizziness, facial flushing, nausea, anxiety, increased appetite, augmented sweat, insomnia, and disturbed stomach function. It is advised to visit your doctor if you may start to experiencing any severe side effects.


Note Underlined Mentioned Contraindications for Prednisolone -

  1. If you are allergic to Prednisolone or have any form of fungal infection then you should not use this medication.
  2. The medicine is contraindicated if you are suffering from liver disease, kidney disease; a thyroid disorder; diabetes; or a history of malaria.
  3. Prednisolone belongs to FDA pregnancy category C. You must tell your doctor if you are pregnant, breast feeding or plan to become pregnant while being on this medication.


Drug Interaction of Prednisolone -

The medicine is contraindicated with medication such as Clarithromycin, ephedrine, aspirin, cyclosporine, estrogens, oral contraceptives, Furosemide, Quinolone antibiotics, hydantoins carbamazepine, hydrochlorothiazide, Mifepristone due to potential health risk.


Essential Precautionary measure to followed with Prednisolone -

  1. Do not discontinue Prednisolone abruptly, ask your doctor how to avoid withdrawal symptoms.
  2. Tell your physician about any medical condition or infection within the past.
  3. Medicine is not indicated to children under 18 without doctors recommendation.
  4. Avoid alcohol while you are using Prednisolone.
  5. Do not receive a live vaccine while taking Prednisolone.

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