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Anafranil is one such renowned medications that help patients in defeating the distress of obsessive-compulsive disorder. It is a distinguished medication which aids patients in suppressing continual/undesired thoughts, and longing to execute repeated tasks as like of hand washing, checking, counting etc. which hamper daily living of an individual. It accommodates generic Clomipramine as its essential component which by affecting the chemicals in the brain that may be off balance exhibits its unbeatable effects.


Mechanism of action of Anafranil:

Anafranil (Clomipramine) works by improving the actions of serotonin and norepinephrine via impeding their reuptake and extending their activity. It also has anticholinergic characteristics and thus it obstructs the action of another neurotransmitter named as acetylcholine. It also exhibits weak antihistamine properties which known to play a role in the mild sedative effects seen with Clomipramine use.


Dosing regimen of Anafranil:

Initially, a patient is suggested to start treatment with a 25mg dose daily which should be steadily titrated, as tolerated to a dose of 100mg during the first 2 weeks. While initial titration, it should be taken in divided doses with food to lessen gastrointestinal side effects. Subsequently, the dosage over the next several weeks may be titrated gradually up to an utmost dose strength of 250mg daily. After increment, the total daily dose may be taken once daily at bedtime to diminish daytime drowsiness.


Opposing factors with Anafranil:

In the presence of medical ailments such as low blood pressure, narrow-angle glaucoma, liver or kidney disease, seizures, heart disease, urinating problems or hypersensitivity to Clomipramine or to any other similar antidepressants a patient should not follow treatment with Anafranil.


Annoying effects of Anafranil:

Some of the annoying effects that you may struggle while using Anafranil include vision changes, dizziness, sleepiness, nausea, upset stomach, constipation, dry mouth, insomnia, numbness or tingling or trouble in concentrating.


Defensive steps that should be remembered with Anafranil:

  • Do not booze alcohol else sever malicious effects can be experienced.
  • Evade participating in any action after consuming Anafranil that wants you to be aware as you may likely to have dizzy or drowsy like adverse effects.
  • Eschew using this medicine if you are a pregnant or lactating woman.
  • Never offer this remedy to anyone who is less than 18 years old.

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